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Highlighting GI Disorders with Leonard Weinstock, M.D.

Updated: Oct 4, 2021

Gastrointestinal Problems

Are you suffering from gastrointestinal distress?

Are you somewhere on the hypermobility spectrum? Did you know that people with hypermobility disorders have a higher prevalence of GI problems than the general population?

A Gastroenterologist's Perspective

Dr. Leonard Weinstock, board-certified gastroenterologist with expertise in Ehlers-Danlos syndromes (EDS) and related disorders, sits down with Bendy Bodies to discuss this very topic. Dr. Weinstock discusses the “unhappy triad" of EDS, postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS) and how MCAS may actually be at the heart of EDS. He lists ways to be evaluated for GI disorders and speculates that 10-17% of the general population may have undiagnosed MCAS. He stresses the importance of a multi-disciplinary approach to treatment and thinking outside the box.

Topics Covered

  • Gastroparesis

  • Small bowel intestinal overgrowth (SIBO) Median arcuate ligament syndrome (MALS)

  • Mast Cell Activation Syndrome (MCAS)

  • Postural Orthostatic Tachycardia Syndrome (POTS)

  • Low-dose naltrexone (LDN)

  • Endorphin production

  • Inflammation

  • Supplements

  • Dietary changes


As one of the authors of "Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome", Dr. Weinstock discusses the possible link between long-COVID 19 illness and MCAS. And finally, he shares suggestions on what to do if you’re having difficulty finding a GI specialist who understands complicated disorders like EDS and MCAS. For anyone dealing with GI issues, as well as physicians looking to understand the connection between hypermobility and GI disorders, this is a timely and important podcast.

Episode transcript:

Episode 34 - Highlighting GI Disorders with Leonard Weinstock, MD
Download PDF • 159KB



Access the "MCAS Validated Questionnaire" referred to by Dr. Weinstock.


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