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Are Mast Cells Driving Autism? with Dr. Pejman Katiraei  (Ep 145)
01:22:43

Are Mast Cells Driving Autism? with Dr. Pejman Katiraei (Ep 145)

What if the diagnosis was just the beginning—and the root cause was hiding in plain sight? In this riveting episode, Dr. Linda Bluestein welcomes pediatrician and integrative medicine expert Dr. Pejman Katiraei, whose work with children struggling with autism, mold exposure, and mast cell activation reveals a shocking truth: many kids aren’t just neurodivergent—they have neuroinflammation. Together, they peel back the layers on what’s really driving autistic behaviors, why some children can’t tolerate food, noise, or even hugs—and how mast cells and histamine might be behind it all. Dr. Katiraei shares remarkable stories of transformation, explains why traditional testing often fails, and reveals a controversial treatment that’s changing lives. If your child is sensitive, reactive, or struggling to connect—and you’ve been told it’s just "behavioral"—this conversation might rewrite what you thought was possible. Takeaways: One child's refusal to eat broccoli held more answers than anyone expected. Could colic be the first warning sign of central inflammation? He couldn’t feel love—until one unlikely medication changed everything. A house tested clean… but the child kept getting worse. Why? Some diagnoses miss what’s burning beneath the surface. Reference Links: ⁠https://pubmed.ncbi.nlm.nih.gov/18626069/⁠ ⁠https://www.sciencedirect.com/science/article/abs/pii/S0941950014001936⁠ The Dust Test ⁠https://www.thedusttest.com/⁠ ⁠https://www.mayoclinic.org/drugs-supplements/itraconazole-oral-route/description/drg-20071421⁠ ⁠https://www.sciencedirect.com/science/article/abs/pii/S0149291813001823⁠ ⁠https://pmc.ncbi.nlm.nih.gov/articles/PMC10932299/⁠ Watch Ep 32 with Dr. Jessica Eccles: ⁠https://youtu.be/BmIFATctyzk⁠ Watch Ep 47 with Dr. Jessica Eccles: ⁠https://youtu.be/nhsLDzLpUWE⁠ Watch Ep 139 with Dr. Theoharides: ⁠https://youtu.be/u1pxvAzXh7M⁠ Connect with YOUR Hypermobility Specialist, Dr. Linda Bluestein, MD at ⁠https://www.hypermobilitymd.com/⁠. Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠https://www.bendybodiespodcast.com/⁠. YOUR bendy body is our highest priority! ⁠https://wholistickids.com/⁠ ⁠https://www.wholisticminds.com/⁠ ⁠https://pkatiraei.substack.com⁠ ⁠https://www.youtube.com/@pkatiraei ⁠https://www.instagram.com/wholistickids?igsh=MXNyd3I3NTc0aGIydw==⁠ Use this affiliate link for Algonot to get an extra 5% off your entire order: ⁠https://algonot.com/coupon/bendbod/⁠ FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links. Connect with the HypermobilityMD: YouTube: ⁠youtube.com/@bendybodiespodcast⁠  Instagram: ⁠https://www.instagram.com/hypermobilitymd/⁠ ⁠ Facebook: https://www.facebook.com/BendyBodiesPodcast⁠  X: ⁠https://twitter.com/BluesteinLinda⁠  LinkedIn: ⁠https://www.linkedin.com/in/hypermobilitymd/⁠  Newsletter: ⁠https://hypermobilitymd.substack.com/⁠ Shop my Amazon store ⁠https://www.amazon.com/shop/hypermobilitymd⁠ Learn more about Human Content at ⁠http://www.human-content.com⁠ Podcast Advertising/Business Inquiries: ⁠sales@human-content.com⁠ Part of the Human Content Podcast Network
Have you ever had your symptoms dismissed as “just anxiety” or “all in your head”?
00:57
Unraveling Fatigue: Exploring ME/CFS and Long COVID (Ep 144)
01:11:20

Unraveling Fatigue: Exploring ME/CFS and Long COVID (Ep 144)

What if your body’s collapse wasn’t burnout… but a system crash no test can catch? In this episode, Dr. Linda Bluestein welcomes Isabelle Ramirez Burnett, systems engineer, health coach, and founder of Renegade Research, to reveal the silent breakdowns behind ME/CFS, long COVID, and hypermobility-related illness. Diagnosed with ME/CFS at just 7 years old, Isabelle pulls back the curtain on decades of missed diagnoses, medical dismissal, and her discovery of a community willing to do what the healthcare system couldn’t—build their own science. You’ll hear about the remission that stunned researchers, the controversial meds that gave her life back, and the protocols patients are building from the ground up. If you’ve ever wondered why your body feels like it’s working against you—or what recovery might actually look like—this episode may change everything. 00:00 Introduction and Guest Introduction 01:53 Isabelle's Personal Journey with ME/CFS 06:07 Challenges in the US Healthcare System 15:08 Becoming an Advocate and Addressing Misconceptions 36:45 Understanding Patient Empowerment 41:07 Managing Symptoms with Medications 52:44 Self-Care Strategies for ME/CFS 56:03 Research and Advocacy for ME/CFS and Long COVID Takeaways: She couldn’t stand in front of the fridge—until a “taboo” medication changed everything. The labs were normal. Her body was screaming. A grandmother, a diagnosis, and an unstoppable fight for answers. What if your symptoms don't show up on any scan… but still hold the truth? The protocol that sparked a remission—and a global movement. Reference Links: RemissionBiome w/Dr. Yellman: https://www.youtube.com/watch?v=D-I8eRxAeZ4&ab_channel=RenegadeResearch https://pmc.ncbi.nlm.nih.gov/articles/PMC7831961/ Connect with YOUR Hypermobility Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/. Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/. YOUR bendy body is our highest priority! About Isabel Ramirez-Burnett : Twitter: https://x.com/isabelramirezrd?lang=en Renegade Research Twitter: https://x.com/renegaderes Youtube: https://www.youtube.com/remissionbiome LinkedIn: https://www.linkedin.com/isabelramirezrd BlueSky: https://isabelramirezrd.bsky.social Amazon: https://amzn.to/3EB7PcC Keep up to date with the HypermobilityMD: Shop my Amazon store https://www.amazon.com/shop/hypermobilitymd Twitter: twitter.com/BluesteinLinda LinkedIn: linkedin.com/in/hypermobilitymd Facebook: facebook.com/BendyBodiesPodcast Blog: hypermobilitymd.com/blog Learn more about Human Content at http://www.human-content.com Podcast Advertising/Business Inquiries: sales@human-content.com Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links. **Disclaimer:** The content shared in this video is meant for general information only and is not intended as medical advice, diagnosis, or treatment. Always speak with a qualified healthcare provider regarding any questions you may have about a medical condition or treatment plan. The information presented here should not be used as a replacement for professional medical guidance. Any mentions of specific products are not intended to diagnose, treat, cure, or prevent any disease.
Dental Problems in EDS with Dr. Audrey Kershaw (Ep 143)
01:12:56

Dental Problems in EDS with Dr. Audrey Kershaw (Ep 143)

What if your dental history held the key to a complex diagnosis no one’s caught? In this gripping episode of the Bendy Bodies Podcast, Dr. Linda Bluestein welcomes Dr. Audrey Kershaw, a trailblazing oral surgeon who’s uncovered hundreds of hidden Ehlers-Danlos Syndrome (EDS) cases—starting in the dental chair. From patients who “can’t numb up,” to decades-long battles with halitosis, gum fragility, and jaw instability, Dr. Kershaw shares the subtle (and sometimes shocking) signs that suggest something far deeper is at play. Together, they explore what happens when TMD, failed anesthesia, slow healing, and even bad breath point to connective tissue disorders that most dentists never learn about. If your mouth has always felt... different—this episode might explain why. Takeaways: Some patients can’t numb up… and the reason may change how you see your entire body. Your wisdom tooth extraction might’ve revealed more than just a dental issue. That persistent jaw pain? It may be pointing to something systemic. A 40-year case of bad breath led to an unexpected diagnosis—here’s what happened. You might be able to spot a connective tissue disorder… before a dentist even says a word. Reference Links: GIRFT RCS TMD full document. https://www.rcseng.ac.uk/-/media/FDS/Comprehensive-guideline-Management-of-painful-Temporomandibular-disorder-in-adults-March-2024.pdf GITFT RCS TMD patient summary document. https://www.rcseng.ac.uk/-/media/FDS/TMD-Patient-support-document-March-2024.pdf GIRFT RCS TMD Clinician summary document https://www.rcseng.ac.uk/-/media/FDS/TMD-Clinician-summary-document-March-2024.pdf Scottish Dental Magazine article EDS Article https://oralsurgeryscotland-my.sharepoint.com/personal/hello_oralsurgery_scot/_layouts/15/onedrive.aspx BISOM link to mouth ulcers https://bisom.org.uk/wp-content/uploads/2020/02/RAS-PIL-October-2019.pdf LA paper 2019 https://pmc.ncbi.nlm.nih.gov/articles/PMC6834718/ Link to pt EDS email EDS PATIENT EMAIL April 2025.docx Link to "Perioperative Management of Patients with Ehlers-Danlos Syndromes" by Drs. Chopra and Bluestein https://www.scirp.org/journal/paperinformation?paperid=97524 Connect with YOUR Hypermobility Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/. Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/. YOUR bendy body is our highest priority! Learn about Dr. Audrey Kershaw: Website: https://www.oralsurgery.scot/ Keep up to date with the HypermobilityMD: Shop my Amazon store https://www.amazon.com/shop/hypermobilitymd Twitter: twitter.com/BluesteinLinda LinkedIn: linkedin.com/in/hypermobilitymd Facebook: facebook.com/BendyBodiesPodcast Blog: hypermobilitymd.com/blog Learn more about Human Content at http://www.human-content.com Podcast Advertising/Business Inquiries: sales@human-content.com Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links. **Disclaimer:** The content shared in this video is meant for general information only and is not intended as medical advice, diagnosis, or treatment. Always speak with a qualified healthcare provider regarding any questions you may have about a medical condition or treatment plan. The information presented here should not be used as a replacement for professional medical guidance. Any mentions of specific products are not intended to diagnose, treat, cure, or prevent any disease.
Is Your EDS Party Trick Causing Long-Term Damage? | Office Hours (EP 142)
44:03

Is Your EDS Party Trick Causing Long-Term Damage? | Office Hours (EP 142)

What if the very things you do to feel or look better are quietly making you feel worse? In this solo episode of the Bendy Bodies Podcast, Dr. Linda Bluestein answers listener questions—but what begins as a practical Q&A quickly dives into rarely discussed truths about cosmetic procedures, EMFs, neuroinflammation, and even fragrances as dangerous triggers. You’ll hear surprising stories from patients who’ve suffered unexpected complications—and discover how seemingly harmless habits, like party tricks or perfume, could be tipping the scale toward long-term damage. Plus, Dr. Bluestein unpacks the case for renaming MCAS, the underrecognized connection between transness and hypermobility, and why your surgeon might not be as EDS-aware as they claim. If you think you’ve already heard it all about EDS (Ehlers-Danlos Syndromes), HSD (Hypermobility Spectrum Disorders), MCAS (Mast Cell Activation Syndrome), and chronic illness—you haven’t heard this. Takeaways: You might be surprised to learn which test isn’t as useful for diagnosing MCAS as people think. The brain fog you're feeling? There's a cellular player involved—and it's not just inflammation. Some reactions you're calling “allergies” might be something very different (and trickier to detect). The way mast cells interact with the brain could change how we think about neurodevelopment. A few supplements could help—but only if you're asking the right questions first. Chapters: 00:00 Introduction and Welcome 01:17 Testosterone Therapy Insights 05:56 Cosmetic Treatments and EDS 12:41 Raynaud's Syndrome and Small Fiber Neuropathy 18:16 Transness and Hypermobility 21:35 Mast Cell Activation Spectrum 25:17 Fragrances, EMFs, and Party Tricks Connect with YOUR Hypermobility Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/. Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/. YOUR bendy body is our highest priority! LinkedIn: https://www.linkedin.com/in/theoharis-theoharides-ms-phd-md-faaaai-67123735 Keep up to date with the HypermobilityMD: Shop my Amazon store https://www.amazon.com/shop/hypermobilitymd Twitter: twitter.com/BluesteinLinda LinkedIn: linkedin.com/in/hypermobilitymd Facebook: facebook.com/BendyBodiesPodcast Blog: hypermobilitymd.com/blog Learn more about Human Content at http://www.human-content.com Podcast Advertising/Business Inquiries: sales@human-content.com Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links. **Disclaimer:** The content shared in this video is meant for general information only and is not intended as medical advice, diagnosis, or treatment. Always speak with a qualified healthcare provider regarding any questions you may have about a medical condition or treatment plan. The information presented here should not be used as a replacement for professional medical guidance. Any mentions of specific products are not intended to diagnose, treat, cure, or prevent any disease.

Videos:

Publications:

Why double-jointed people are more likely to have health problems

Author: Rachel Fairbank

 

Why do I hurt? Gaining a better grasp on hypermobility and Ehlers-Danlos Syndrome

Author: Jackie Duda

MDs With Chronic Illness Live in a Different Medical World

Author: Sarah Yahr Tucker

 

Does Hypermobility Make You More Prone to Sports Injuries?

Author: Beth Krietsch

 

Hope for Hypermobility: Part 2-An Integrative Approach to Treating Symptomatic Joint Hypermobility

Author: Victoria Daylor, BFA, Cortney Gensemer, PhD, Russell Norris, PhD, and Linda Bluestein, MD.

 

Hope for Hypermobility: Part 1-An Integrative Approach to

Treating Symptomatic Joint Hypermobility

Author: Victoria Daylor, BFA, Cortney Gensemer, PhD, Russell Norris, PhD, and Linda Bluestein, MD.

 

Millions have the same 'bendy body' disease as my daughter. Why isn't the medical profession paying more attention?

Author: Sarah Lazarus

My daughter and COVID: a tale of 3 doctors

Author: Laura Fernando and Linda Bluestein, MD  

 

What a lifetime of gaslighting by other doctors feels like

Author: Sarah Cohen, MD and Linda Bluestein, MD  

The journey to diagnosing a mysterious illness

Author: Linda Bluestein, MD and Lauren Vasko

 

Besides Being Bendy, Hypermobile Dancers May Experience These Surprising Symptoms

Author: Linda Bluestein, MD

The difficult to diagnose comorbidity that plagues Ehlers-Danlos syndrome patients 

Author: Linda Bluestein, MD and Julie Griffis, PT

Inflammation in the Dancer

Author: Linda Bluestein

The Dancer's Planning Guide to Optimizing Immunity During COVID-19 and Beyond 

Author: Linda S. Bluestein

Diagnosis of mast cell activation syndrome: a global “consensus-2” 

Authors:  Lawrence B. Afrin, Mary B. Ackerley, Linda S. Bluestein et al

"Disjointed | Navigating the Diagnosis and Management of hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders"

Editor: Diana Jovin, Contributors: Paldeep Atwal, M.D., Richard Barnum, M.D., Linda Bluestein, M.D. et al

 

Pain Management in Patients with Hypermobility Disorders

Author: Linda Bluestein 

Perioperative Care in Patients with Ehlers Danlos Syndromes

Authors: Pradeep Chopra and Linda Bluestein 

Understanding Hypermobility in Dancers

Author: Linda Bluestein for Healthy Dancer Canada

Anesthesia and Surgery Safety Card

Created by Linda Bluestein 


 

Podcast Guest Appearances:

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#480 Hypermobility with Dr. Linda Bluestein

The Curbsiders Internal Medicine Podcast

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The Role of Interventionalists for Bendy Bodies.

Pain Unfiltered Podcast

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Beyond Flexibility: Recognizing and Supporting Hypermobility in Dancers.

The Acrobatic Arts Podcast

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003- Dr. Linda Bluestein M.D.-Hypermobility, Ehlers Danlos Syndrome, and Why You Are Stronger Than You Believe.

 Whealth Podcast

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The Link Between Hypermobility Spectrum Disorders, Hypermobile-EDS, MCAS, and Endometriosis with Dr Linda Bluestein

This EndoLife

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If you can't connect the issues, think connective tissues 

The Podcast by Kevin MD

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Hypermobility Problems with Anesthesiologist Dr. Linda Bluestein

Knock Knock, Hi! with the Glaucomfleckens Podcast

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Hypermobility: Separating Fact From Fiction with Dr. Linda Bluestein

Acrobatic Arts Podcast

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Ehlers-Danlos Syndrome and Beyond - Health Connections You Need to Know with Dr. Linda Bluestein

Becoming Immune Confident Podcast

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Holistic Approaches to Navigating Ehlers-Danlos Syndrome, POTS, and MCAS

Modern Pain Podcast

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Pain and Hypermobility with Dr. Linda Bluestein - Mast Cell Matters Series

The POTSCAST

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Hypermobility Disorders: The Power of Proactivity with Linda Bluestein, MD

Acrobatic Arts Podcast

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Treatment Room Secrets #19 - Dr. Linda Bluesteim M.D. - Hypermobility

Treatment Room Secrets Podcast

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Case #05: Kyle
With Dr. Linda Bluestein

Symptomatic: A Medical Mystery Podcast

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Hypermobility Spectrum Disorders with Dr. Linda Bluestein

Redefining Yoga

Schedule an Event
with the Hypermobility M.D.

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Content is for informational purposes only and should not be interpreted as a substitute for medical advice. The Hypermobility MD shall not be held liable for any visitor's use of this site's content. Content on this website should always be used with the participation of your licensed healthcare professional.

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