No, calling EDS or HSD "benign" is one of the most persistent and harmful myths about these conditions. The older term "Benign Joint Hypermobility Syndrome" has been abandoned because it does not reflect the significant impact these conditions can have.
People with EDS and HSD can experience persistent pain, over 20 different causes of headache pain, and involvement of virtually every bodily system. Comorbid conditions such as dysautonomia, POTS, and mast cell activation syndrome are common. While EDS/HSD may not be "malignant" in the traditional sense, it is far from benign.